1638250-96-0 Usage
Uses
1,2,3,6-Tetrahydro-1,3-dimethyl-2,6-dioxo-N-(6-phenyl-3-pyridazinyl)-7H-purine-7-acetamide is a novel potent PORCN inhibitor that blocks the secretion and activity of all Wnts.
Check Digit Verification of cas no
The CAS Registry Mumber 1638250-96-0 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,6,3,8,2,5 and 0 respectively; the second part has 2 digits, 9 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 1638250-96:
(9*1)+(8*6)+(7*3)+(6*8)+(5*2)+(4*5)+(3*0)+(2*9)+(1*6)=180
180 % 10 = 0
So 1638250-96-0 is a valid CAS Registry Number.
1638250-96-0Relevant articles and documents
COMBINATION THERAPY
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Page/Page column 31, (2021/07/17)
The present invention relates generally to new chemical combinations and methods for their use in the treatment of cancer. In particular, the present invention relates to a particular Wnt modulator, i.e. a compound of formula (I), or a pharmaceutically acceptable salt, solvate or prodrug thereof in combination with a PARP inhibitor for use in the treatment of cancer.
