1638539-65-7 Usage
Description
(S)-tert-butyl 4-((S)-3-(tert-butoxycarbonylamino)-4-hydroxybutyl)-2,2-dimethyloxazolidine-3-carboxylate is a complex chiral molecule with a bulky tert-butyl substituent and an oxazolidine ring, featuring a carbamate and hydroxyl group. It is a sterically hindered compound with potential applications in medicinal chemistry and as a building block for more complex organic molecules.
Uses
Used in Pharmaceutical Industry:
(S)-tert-butyl 4-((S)-3-(tert-butoxycarbonylamino)-4-hydroxybutyl)-2,2-dimethyloxazolidine-3-carboxylate is used as an intermediate in the synthesis of pharmaceutical compounds due to its unique structural features and functional groups, which can be further modified to create new drugs with specific therapeutic properties.
Used in Medicinal Chemistry:
(S)-tert-butyl 4-((S)-3-(tert-butoxycarbonylamino)-4-hydroxybutyl)-2,2-dimethyloxazolidine-3-carboxylate is used as a chiral building block for the development of novel bioactive molecules. Its stereochemistry and steric hindrance can be exploited to design molecules with improved selectivity and potency in targeting specific biological receptors or enzymes.
Used in Organic Synthesis:
(S)-tert-butyl 4-((S)-3-(tert-butoxycarbonylamino)-4-hydroxybutyl)-2,2-dimethyloxazolidine-3-carboxylate is used as a versatile starting material for the synthesis of complex organic molecules. Its functional groups and structural features can be utilized in various chemical reactions to construct a wide range of compounds with diverse applications in materials science, agrochemicals, and other fields.
Check Digit Verification of cas no
The CAS Registry Mumber 1638539-65-7 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,6,3,8,5,3 and 9 respectively; the second part has 2 digits, 6 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 1638539-65:
(9*1)+(8*6)+(7*3)+(6*8)+(5*5)+(4*3)+(3*9)+(2*6)+(1*5)=207
207 % 10 = 7
So 1638539-65-7 is a valid CAS Registry Number.
1638539-65-7Relevant articles and documents
Synthesis of bis-α-amino acids through proline catalyzed asymmetric α-amination of higher homologs of Garner's aldehyde
Petakamsetty, Ramu,Das, Ram Pada,Ramapanicker, Ramesh
, p. 9554 - 9563 (2014)
A very convenient synthesis of bis-α-amino acids from the higher homologs of Garner's aldehyde is reported. The key step is proline catalyzed asymmetric amination of the aldehydes using dibenzylazodicarboxylate. The aldehydes used are either commercially available or can easily be prepared from aspartic or glutamic acid. One of the two chiral centers in the bis-amino acids comes from the aldehyde and the other one is generated through the proline catalyzed reaction, which were high yielding and proceeded with very high diastereoselectivity (93-99%). The reported route offers a general method for the synthesis of the title compounds with desired stereochemical outcome.
