1639342-46-3

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• 123-54-6 acetylacetone 
• 192818-72-7 (E)-1-fluoro-2-(2-nitrovinyl)benzene 
• 399-25-7 1-fluoro-2-(2-nitro-vinyl)-benzene 

Relevant academic research and scientific papers

Asymmetric Michael addition reactions catalyzed by calix[4]thiourea cyclohexanediamine derivatives

A number of upper rim-functionalized calix[4]thiourea cyclohexanediamine derivatives have been designed, synthesized and used as catalysts for enantioselective Michael addition reactions between nitroolefins and acetylacetone. The optimal catalyst 2 with

Ferrocenophane-based bifunctional organocatalyst for highly enantioselective Michael reactions

Highly enantioselective Michael reactions between acetylacetone and trans-β-nitroolefins are achieved by a novel ferrocenophane-based tertiary amine-thiourea organocatalyst to provide the corresponding products in good to excellent yields (up to 95%) and

Calix[4]thiourea diaminocyclohexane derivatives and method thereof for catalyzing asymmetric Michael addition

The invention relates to calix[4]thiourea diaminocyclohexane derivatives and a method thereof for catalyzing asymmetric Michael addition. An Michael addition catalytic reaction is performed on nitroolefin and 1,3-dicarbonyl ketone as raw materials, the ca

Based on the double function of ferrocene hydrogen bond organic catalyst and its preparation method and application

The invention discloses a double functional hydrogen bond organic catalyst based on ferrocene as well as a preparation method and an application of the double functional hydrogen bond organic catalyst. A structural formula of the catalyst is shown in the

Calixarene-derived chiral tertiary amine-thiourea organocatalyzed asymmetric Michael additions of acetyl acetone and dimethyl malonate to nitroolefins

Novel bifunctional chiral thiourea-tertiary amines bearing a calix[4]arene scaffold were synthesized and applied in catalytic asymmetric Michael addition of acetyl acetone and dimethyl malonate to nitroolefins. The corresponding adducts were obtained in e

1,3-Diamine-Derived Bifunctional Organocatalyst Prepared from Camphor

Chiral 1,2-diamines are privileged structural motifs in organocatalysis, whereas efficient 1,3-diamine-derived organocatalysts are very rare. Herein we report a highly efficient camphor-1,3-diamine-derived squaramide organocatalyst. Its catalytic activity

Novel ferrocene-based bifunctional amine-thioureas for asymmetric Michael addition of acetylacetone to nitroolefins

An efficient method was developed to synthesize ferrocene-based bifunctional amine-thioureas bearing multiple hydrogen-bonding donors. Asymmetric Michael addition of acetylacetone to nitroolefins catalyzed by these novel bifunctional catalysts affords the Michael adducts in high yield and moderate to excellent enantioselectivities. Multiple hydrogen-bonds play an important role in accelerating the reaction.

Ferrocene analogues of hydrogen-bond-donor catalysts: An investigative study on asymmetric Michael addition of 1,3-dicarbonyl compounds to nitroalkenes

This report describes the synthesis of eight ferrocene derivatives of squaramide- or thiourea- based bifunctional catalysts containing cinchona alkaloid moieties. A stepwise sequential route was used to assemble the various components of these ferrocene d

Ferrocene as a scaffold for effective bifunctional amine-thiourea organocatalysts

A simple and readily accessible prototype of the ferrocene-based bifunctional amine-thioureas shows high enantioselectivity in the Michael addition of acetylacetone to nitroolefins, giving the enantioselectivity of up to 96% ee. This work demonstrates tha