1639394-81-2Relevant academic research and scientific papers
Unnatural amino acids increase activity and specificity of synthetic substrates for human and malarial cathepsin C
Poreba, Marcin,Mihelic, Marko,Krai, Priscilla,Rajkovic, Jelena,Krezel, Artur,Pawelczak, Malgorzata,Klemba, Michael,Turk, Dusan,Turk, Boris,Latajka, Rafal,Drag, Marcin
, p. 931 - 943 (2014/05/06)
Mammalian cathepsin C is primarily responsible for the removal of N-terminal dipeptides and activation of several serine proteases in inflammatory or immune cells, while its malarial parasite ortholog dipeptidyl aminopeptidase 1 plays a crucial role in ca
