1639790-33-2

Upstream product

• 873-77-8 (4-chlorphenyl)magnesium bromide 
• 45941-96-6 2-(4-chlorophenyl)-3-hydroxypropene 
• 541-41-3 chloroformic acid ethyl ester 

Downstream Products

• 1639790-55-8 5-(4-chlorophenyl)-3-(1,3-dithiolan-2-ylidene)hex-5-en-2-one 
• 1639790-60-5 (E)-6-(4-chlorophenyl)-4-(1,3-dithiolan-2-ylidene)-1-phenylhepta-1,6-dien-3-one 
• 1639790-61-6 (E)-1,6-bis(4-chlorophenyl)-4-(1,3-dithiolan-2-ylidene)hepta-1,6-dien-3-one 

Relevant academic research and scientific papers

Palladium-catalyzed oxidative heck-type allylation of β,β- disubstituted enones with allyl carbonates

The palladium-catalyzed oxidative Heck-type allylation of β,β-disubstituted enones, i.e., α-oxoketene dithioacetals, was efficiently realized with allyl carbonates, providing a concise route to highly functionalized dienes. The present synthetic methodology utilizes the substrate activation strategy to activate the C-H bond of β,β-disubstituted enones by introduction of a 1,2-dithiolane functionality to make the enone substrate highly polarized and thus increase its reactivity, demonstrating rare examples for transition metal-catalyzed allylic substitution of ss,ss-disubstituted enones through a Heck-type allylation process.