163982-62-5

Basic information

• Product Name: 2(3H)-Benzothiazolone, 6-(2-fluorobenzoyl)-
• CAS NO: 163982-62-5
• Molecular Formula: C14H8FNO2S
• Molecular Weight: 273.287
• Mol File: 163982-62-5.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 2(3H)-Benzothiazolone, 6-(2-fluorobenzoyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: 2(3H)-Benzothiazolone, 6-(2-fluorobenzoyl)-(163982-62-5)
• EPA Substance Registry System: 2(3H)-Benzothiazolone, 6-(2-fluorobenzoyl)-(163982-62-5)

Safety Data

• Hazardous Substances Data: 163982-62-5(Hazardous Substances Data)

Upstream product

• 934-34-9 2(3H)-Benzothiazolone 
• 445-29-4 o-fluoro-benzoic acid 

Downstream Products

• 1148013-64-2 C₁₈H₁₄FNO₄S 

Relevant articles and documents

Amide derivatives of [6-acyl-2-benzothiazolinon-3-yl] acetic acids as potential analgesic and anti-inflammatory compounds

In this study, we investigated the analgesic and anti-inflammatory activities of [6-acyl-2-benzothiazolinon-3-yl]acetic acids by the derivatization of the carboxylate moiety into amides. We have tested the analgesic and anti-inflammatory activities of the synthesized compounds in vivo by using p-benzoquinone-induced writhing test and carrageenan-induced hind paw edema model, respectively. Compounds 4h, 4i, 4n, and 4o showed comparable analgesic and anti-inflammatory activities to the references without gastric lesions in the tested animals. In addition, all compounds also tested for their inhibitory activity against cyclooxygenase (COX)-1, COX-2 and 5-lipoxygenase (LOX), but no significant inhibition was observed under assayed conditions.