1639843-33-6 Usage
General Description
DI-FMOC-SELENO-L-CYSTINE is a chemical compound that contains selenocysteine, an amino acid with a selenium atom in place of the sulfur atom found in cysteine. The compound is often used in peptide synthesis and proteomics research due to its ability to form stable disulfide bonds and its potential antioxidant properties. The "DI-FMOC" prefix indicates the presence of a 9-fluorenylmethyloxycarbonyl (Fmoc) protecting group, which is commonly used in peptide synthesis to protect the amino group and allow for selective deprotection during the synthesis process. Overall, DI-FMOC-SELENO-L-CYSTINE is a valuable tool in the study and manipulation of proteins and peptides.
Check Digit Verification of cas no
The CAS Registry Mumber 1639843-33-6 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,6,3,9,8,4 and 3 respectively; the second part has 2 digits, 3 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 1639843-33:
(9*1)+(8*6)+(7*3)+(6*9)+(5*8)+(4*4)+(3*3)+(2*3)+(1*3)=206
206 % 10 = 6
So 1639843-33-6 is a valid CAS Registry Number.
1639843-33-6Relevant articles and documents
A comprehensive one-pot synthesis of protected cysteine and selenocysteine SPPS derivatives
Flemer, Stevenson
, p. 1257 - 1264 (2015/04/14)
A proof-of-principle methodology is presented in which all commercially-available cysteine (Cys) and selenocysteine (Sec) solid phase peptide synthesis (SPPS) derivatives are synthesized in high yield from easily prepared protected dichalcogenide precursors. A Zn-mediated biphasic reduction process applied to a series of four bis-Nα-protected dichalcogenide compounds allows facile conversion to their corresponding thiol and selenol intermediates followed by insitu S- or Se-alkylation with various electrophiles to directly access twenty one known Cys and Sec SPPS derivatives. Most of these derivatives were able to be precipitated in crude form out of petroleum ether in sufficient purity for direct use as peptide building blocks. Subsequent incorporation of these derivatives into peptide models nicely illustrates their viability and applicability toward SPPS.
