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16409-34-0

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16409-34-0 Usage

Description

Sodium deoxyglycolic acid is a kind of bile salt, and exists in bile in the form of combining with glycine or taurine to form glycodeoxycholic acid or sodium taurodeoxycholate. It is cholanoic acid that forms many organic compounds and stable molecular compounds.

Synthesis

Sodium deoxyglycolic acid is easily soluble in water and has a strong surface activity. It can be used to destroy cells to extract enzymes. Sodium deoxyglycolic acid is not directly biosynthesized by cholesterol, but is metabolized by intestinal bacteria. Synthesized from cholic acid.

Physical properties

Solid

Uses

Sodium glycodeoxycholate has been used in a study to develop more similar mimetic intestinal fluids to physiological fluids than those developed by mixed bile salt systems (MBS). It has also been used in a study to investigate Ca2+ buffering capability of bile salt micelles.

General Description

Sodium glycodeoxycholate is a bile salt that can be used to form biomimicking environments.

Biochem/physiol Actions

Induces apoptosis in hepatocytes; may induce DNA cleavage.

Check Digit Verification of cas no

The CAS Registry Mumber 16409-34-0 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,6,4,0 and 9 respectively; the second part has 2 digits, 3 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 16409-34:
(7*1)+(6*6)+(5*4)+(4*0)+(3*9)+(2*3)+(1*4)=100
100 % 10 = 0
So 16409-34-0 is a valid CAS Registry Number.
InChI:InChI=1/C26H43NO5.Na/c1-15(4-9-23(30)27-14-24(31)32)19-7-8-20-18-6-5-16-12-17(28)10-11-25(16,2)21(18)13-22(29)26(19,20)3;/h15-22,28-29H,4-14H2,1-3H3,(H,27,30)(H,31,32);/t15-,16-,17-,18+,19-,20+,21+,22+,25+,26-;/m1./s1

16409-34-0 Well-known Company Product Price

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  • (Code)Product description
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  • Packaging
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  • TCI America

  • (S0937)  Sodium Glycodeoxycholate  >97.0%(HPLC)(N)

  • 16409-34-0

  • 200mg

  • 390.00CNY

  • Detail
  • TCI America

  • (S0937)  Sodium Glycodeoxycholate  >97.0%(HPLC)(N)

  • 16409-34-0

  • 1g

  • 1,350.00CNY

  • Detail

16409-34-0Relevant articles and documents

Continuous flow synthesis and scale-up of glycine- and taurine-conjugated bile salts

Venturoni, Francesco,Gioiello, Antimo,Sardella, Roccaldo,Natalini, Benedetto,Pellicciari, Roberto

experimental part, p. 4109 - 4115 (2012/06/15)

A multi-gram scale protocol for the N-acyl amidation of bile acids with glycine and taurine has been successfully developed under continuous flow processing conditions. Selecting ursodeoxycholic acid (UDCA) as the model compound and N-ethoxycarbonyl-2-ethoxy-1,2-dihydroquinoline (EEDQ) as the condensing agent, a modular mesoreactor assisted flow set-up was employed to significantly speed up the optimization of the reaction conditions and the flow scale-up synthesis. The results in terms of yield, in line purification, analysis, and implemented flow set-up for the reaction optimization and large scale production are reported and discussed.

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