164105-98-0

Upstream product

• 163964-60-1 ((4R,5S)-2,2-dimethyl-1,3-dioxolane-4,5-diyl)bis(methylene) bis-(2,2-dimethylpropanoate) 
• 136136-22-6 ((4R,5S)-5-(hydroxymethyl)-2,2-dimethyl-1,3-dioxolan-4-yl)methyl acetate 
• 55904-12-6 ((4R,5S)-5-Hydroxymethyl-2,2-dimethyl-[1,3]dioxolan-4-yl)-methanol 
• 163964-63-4 Acetic acid (4R,5S)-5-(tert-butyl-diphenyl-silanyloxymethyl)-2,2-dimethyl-[1,3]dioxolan-4-ylmethyl ester 

Relevant academic research and scientific papers

Systematic and Stereoselective Total Synthesis of Mannosylerythritol Lipids and Evaluation of Their Antibacterial Activity

The total synthesis of the 20 homogeneous members of mannosylerythritol lipids (MELs) with different alkyl chain lengths was effectively and systematically accomplished from a strategically designed common key intermediate that was stereoselectively constructed by the borinic acid catalyzed β-mannosylation reaction. In addition, their antibacterial activities against Gram-positive bacteria were evaluated. Our results demonstrated that not only the length of the alkyl chains but also the pattern of Ac groups on the mannose moiety were important factors for antibacterial activity.

ERYTHRITOL : A VERSATILE PRECURSOR FOR C-4 CHIRAL BUILDING BLOCKS

Starting from erythritol, enzyme catalyzed construction of C4 chiral building blocks is described.The four diastereomeric protected tetroses are available from this single compound.Also an approach to L- and D-hexose-derivatives is presented.