164169-42-0Relevant articles and documents
Thioglycoluril as a highly efficient, recyclable and novel organocatalyst for N-Boc protection of amines
Khaksar, Samad,Vahdat, Seyed Mohammad,Tajbakhsh, Mahmood,Jahani, Fatemeh,Heydari, Akbar
experimental part, p. 6388 - 6391 (2011/01/03)
A simple and efficient protocol for the chemoselective mono-N-Boc protection of various structurally diverse amines with di-tert-butyl dicarbonate using thioglycoluril as the catalyst is described. The catalyst can be readily separated from the reaction products by simple filtration and recovered for reuse. No competitive side reactions, such as formation of isocyanate, urea, oxazolidinone, and N,N-di-Boc derivatives were observed.
New N-hydroxy carbamic acid trialkylsilyl derivatives: preparation and thermal reactions
Moertl, M.,Knausz, D.,Boecskei, Zs.,Kolos, Zs.,Ujszaszy, K.,et al.
, p. 115 - 120 (2007/10/02)
New N-siloxy- or N-alkoxy-carbamic acid derivatives have been prepared.The crystal structure of N-siloxy-O-tert-butyl carbamate was determined.The thermal behaviour of these compounds was studied in the absence and in the presence of other reaction partners.The reaction products were identified by gas chromatography, gas chromatography-mass spectroscopy, IR spectroscopy and NMR.The experimental results can be explained by the formation of a radical-type transition state (carboxynitrene), detected by mass spectroscopy.Keywords: Silicon; Nitrene; Trimethylsilyl; Mass spectroscopy; Crystal structure
