164230-52-8 Usage
Chemical structure
A 17-membered ring containing four nitrogen atoms and a ketone group attached to a phenyl ring.
Chirality
It is a chiral molecule with a specific stereochemistry denoted as (8S)-.
Synonyms
(-)-SR-31742.
Functionality
It is a potent and selective antagonist for the group II metabotropic glutamate receptors.
Therapeutic applications
It has been studied for its potential use in the treatment of neurodegenerative disorders, schizophrenia, and other neurological conditions.
Research tool
It may also have potential use as a research tool for studying the role of group II metabotropic glutamate receptors in various physiological and pathological processes.
Check Digit Verification of cas no
The CAS Registry Mumber 164230-52-8 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,6,4,2,3 and 0 respectively; the second part has 2 digits, 5 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 164230-52:
(8*1)+(7*6)+(6*4)+(5*2)+(4*3)+(3*0)+(2*5)+(1*2)=108
108 % 10 = 8
So 164230-52-8 is a valid CAS Registry Number.
164230-52-8Relevant articles and documents
Asymmetric syntheses of the macrocyclic spermine alkaloids (-)-(S)-protoverbine, (-)-(S)-buchnerine, and their naturally occurring congenial alkaloids
Drandarov, Konstantin,Guggisberg, Armin,Hesse, Manfred
, p. 979 - 989 (2007/10/03)
Asymmetric syntheses of the following 17-membered macrocyclic spermine alkaloids are presented: (-)-(S)-protoverbine (= (8S)-8-phenyl-1,5,9,13-tetraazacycloheptadecane-6-one: 1), (+)-(S)-protomethine (=(2S)-2-phenyl-1,5,9,14-tetraazabicyclo[12.3.1]octadec