16424-87-6

Usage

Uses

Used in Fragrance and Flavor Industry:
METHYL 6-ISOTHIOCYANATOHEXANOATE is used as a key component in the production of fragrances and flavors for its distinctive aromatic properties, enhancing the sensory experience of various consumer products.
Used in Organic Synthesis:
In the field of organic synthesis, METHYL 6-ISOTHIOCYANATOHEXANOATE serves as a valuable intermediate, contributing to the creation of a wide range of organic compounds for diverse applications.
Used in Agricultural and Pest-Control Products:
METHYL 6-ISOTHIOCYANATOHEXANOATE is used as an active ingredient in agricultural and pest-control products for its insecticidal and fungicidal properties, helping to protect crops and control pests effectively.
Used in Pharmaceutical Applications:
METHYL 6-ISOTHIOCYANATOHEXANOATE is being studied for its potential use in pharmaceuticals as an antimicrobial and antifungal agent, offering a promising avenue for the development of new treatments and therapies.
Safety Precautions:
It is crucial to handle METHYL 6-ISOTHIOCYANATOHEXANOATE with care, as it is known to cause irritation to the skin, eyes, and respiratory system upon exposure. Proper safety measures should be taken to minimize the risk of adverse effects.

InChI:InChI=1/C8H13NO2S/c1-11-8(10)5-3-2-4-6-9-7-12/h2-6H2,1H3

Upstream product

• 2525-16-8 O-methylcaprolactim 
• 463-71-8 thiophosgene 
• 1926-80-3 methyl 6-aminocaproate hydrochloride 

Downstream Products

• 98998-60-8 methyl 6-thioureidohexanoate 

Relevant academic research and scientific papers

Versatile synthesis of 2′-amino-2′-deoxyuridine derivatives with a 2′-amino group carrying linkers possessing a reactive terminal functionality

2,2′-Anhydrouridine has been successfully converted into the appropriate 2′-amino-2′-deoxyuridine derivatives in a reaction with isothiocyanates obtained from amino acids or α,ω-diaminoalkanes. The initially formed oxazolidine-2-thione ring is cleaved under basic conditions into the corresponding 2′-amino(substituted)-2′-deoxyuridine derivatives. The implemented additional terminal functionality in the substituent attached to the 2′-amino group allows further modifications with e.g., fluorophore moiety.

Novel derivatives of benzimidazole and imidazo-pyridine and their use as medicaments

A compound of the formula wherein the substituents are as defined in the specification and pharmaceutical salts thereof having a good affinity for sub-types of melanocortin receptors making them useful for treating diseases in which such receptors are included such as pain, inflammatory conditions, etc.

SYNTHESIS OF ISOTHIOCYANATES FROM NON-AROMATIC NITROGEN-CONTAINING HETEROCYCLES

Investigation of the reaction of thiophosgene with Δ2-oxazolines I, Δ3-thiazolines II, 4H-benzothiazines III, 2-methoxypentahydro-Δ1-azepine IV, theophylline and caffeine showed that only compounds I and IV reacted to give 2-acyloxyethyl isothiocyanates and methyl 6-isothiocyanatohexanoate.The structure of these products was corroborated by IR, 1H NMR, 13C NMR and mass spectral methods.The suitability of the above-mentioned compounds to react is discussed.