1642596-48-2Relevant academic research and scientific papers
Antimicrobial activities of novel 3-substituted [1,2,4] triazolo[4,3-b]pyridazines derivatives
Ruso, Jayaraman Sembian,Rajendiran, Nagappan,Srinivas, Chowdappa,Murthy, Konappa Narasimha,Soumya, Krishnamurthy
, p. 377 - 380 (2014/08/18)
A noval derivatives of 3-substituted[1,2,4]triazolo[4,3-b]pyridazine (4a-4o) and 7,8,9,10-tetrahydrobenzo[4,5] thieno[2,3-d][1,2,4]triazolo[4,3-b] pyridazine (7a-7l) is prepared by the reaction of heteroaryl hydrazone from the aldehyde and pyridazinohydrazine derivative, followed by subjecting the intermediate directly to oxidative cyclization employing the mixture of Me 4NBr and Oxone. These derivatives were subjected to preliminary antimicrobial activities against microorganism. All these compounds exhibit good to moderate activity.
