164297-19-2Relevant academic research and scientific papers
Mechanistic Studies of the Palladium(II)-Copper(II)-mediated Demercuriation of Cycloalkyl and Cycloalkylmethyl Systems
Wells, Adam P.,Kitching, William
, p. 527 - 536 (2007/10/02)
The likely events involved in the conversion of cyclohexylmethylmercuric chloride into predominantly trans-4-methylcyclohexyl chloride, on treatment with PdCl2-CuCl2 in acetic acid, have been identified by product and deuterium-labelling studies, as well as by the behaviour of probable intermediates.Extension to related cycloalkyl- and cycloalkylmethyl--mercuric chloride is reported, and mechanistic changes as a function of ring size, with elimination-re-addition of being important in cyclohexyl systems, but carbocation formation dominating in cyclooctyl cases.
