1643-43-2

Basic information

• Product Name: Hydrazinecarbothioamide,2-[(5-bromo-2-hydroxyphenyl)methylene]-
• Synonyms: Hydrazinecarbothioamide,2-[(5-bromo-2-hydroxyphenyl)methylene]- ;(E)-2-(5-bromo-2-hydroxybenzylidene)hydrazinecarbothioamide
• CAS NO: 1643-43-2
• Molecular Weight: 250.29
• Mol File: 1643-43-2.mol
• Article Data: 6

Chemical Properties

• Melting Point: 160-162 °C
• Boiling Point: 467.4±14.0 °C(Predicted)
• Density: 1.195±0.06 g/cm3(Predicted)
• CAS DataBase Reference: Hydrazinecarbothioamide,2-[(5-bromo-2-hydroxyphenyl)methylene]- (CAS DataBase Reference)
• NIST Chemistry Reference: Hydrazinecarbothioamide,2-[(5-bromo-2-hydroxyphenyl)methylene]- (1643-43-2)
• EPA Substance Registry System: Hydrazinecarbothioamide,2-[(5-bromo-2-hydroxyphenyl)methylene]- (1643-43-2)

Safety Data

• Hazardous Substances Data: 1643-43-2(Hazardous Substances Data)

Upstream product

• 141-82-2 malonic acid 
• 10354-00-4 5H-dibenzo[a,d]cyclohepten-5-ol 
• 1796-78-7 (5H-dibenzocyclohepten-5-yl)malonic acid 

Downstream Products

• 65779-18-2 3-{4-[2-(2-5H-Dibenzo[a,d]cyclohepten-5-yl-acetylamino)-ethyl]-phenyl}-propionic acid 
• 1425088-86-3 C₂₄H₁₈N₄O₂S 
• 1425088-85-2 C₂₆H₂₃N₃S 
• 1425088-82-9 2-(5H-dibenzo[a,d][7]annulen-5-ylacetyl)-N-(3-nitrophenyl)hydrazinecarbothioamides 
• 1425088-81-8 2-(5H-dibenzo[a,d][7]annulen-5-ylacetyl)-N-(4-ethylphenyl)hydrazinecarbothioamides 
• 147900-34-3 (4R-cis)-3-[(5H-Dibenzo[a,d]cyclohepten-5-yl)acetyl]-4-methyl-5-phenyl-2-oxazolidinone 
• 147900-35-4 (4R,5S)-3-[(R)-2-Azido-2-(5H-dibenzo[a,d]cyclohepten-5-yl)-acetyl]-4-methyl-5-phenyl-oxazolidin-2-one 
• 147900-34-3 (4S,5R)-3-(2-5H-Dibenzo[a,d]cyclohepten-5-yl-acetyl)-4-methyl-5-phenyl-oxazolidin-2-one 
• 597569-66-9 C₂₈H₂₈N₂O₅S 
• 597569-63-6 C₂₇H₂₅FN₂O₅S 
• 65779-17-1 3-{4-[2-(2-5H-Dibenzo[a,d]cyclohepten-5-yl-acetylamino)-ethyl]-phenyl}-propionic acid ethyl ester 

Relevant articles and documents

Clear cut example of preference for a 6-membered ring radical cyclisation over the homologous 5-membered ring radical cyclisation. The reaction of 5-[bromoalkyl]-5H-dibenzo[a,d]cycloheptenes with Bu3SnH

The radical cyclisation reaction of the 5-[2-bromo-ethyl]-5H-dibenzo[a,d]cycloheptene 4 with Bu3SnH and AIBN led to the cyclised hydrocarbon 5 as major product, whereas the bromo-derivative 8 with Bu3SnH and AIBN gave only the straight chain product 9. An explanation based on the conformational rigidity of dibenzo[a,d]cycloheptene system calculated by AMI method is proposed. Copyright

Cyclic amino acids and derivatives thereof

Novel cyclic amino acids which are useful in preparing biologically active peptides as well as a process for the preparation of D and L enantiomers of the cyclic amino acids are described where an N-protected derivative of the racemic cyclic amino acid is treated with (-)cinchonidine and the resulting salt resolved into the desired enantiomers, as well as derivatives thereof and valuable intermediates used in the process.

Pharmaceutical composition having relaxing activity which contains a nitrate ester as active substance

The invention relates to pharmaceutical compositions containing novel nitrate esters, of which it was found that they are useful for the treatment of ischemiatic heart diseases, decompensatio cordis, myocardial infarction and hypertension.