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2-fluoro-N-(p-tolyl)aniline is an organic compound with the chemical formula C13H12FN. It is a derivative of aniline, featuring a fluorine atom at the 2-position and a p-tolyl group (a methyl group attached to a phenyl ring) at the nitrogen atom. 2-fluoro-N-(p-tolyl)aniline is a colorless to pale yellow solid and is soluble in organic solvents. It is used as an intermediate in the synthesis of various pharmaceuticals, agrochemicals, and other specialty chemicals. Due to its reactivity and potential applications, 2-fluoro-N-(p-tolyl)aniline is of interest in the fields of organic chemistry and materials science.

1643-98-7

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1643-98-7 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 1643-98-7 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 1,6,4 and 3 respectively; the second part has 2 digits, 9 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 1643-98:
(6*1)+(5*6)+(4*4)+(3*3)+(2*9)+(1*8)=87
87 % 10 = 7
So 1643-98-7 is a valid CAS Registry Number.

1643-98-7Relevant academic research and scientific papers

Ligand-Free Iron-Catalyzed C-F Amination of Diarylamines: A One-Pot Regioselective Synthesis of Diaryl Dihydrophenazines

Aoki, Yuma,O'Brien, Harry M.,Kawasaki, Hiroto,Takaya, Hikaru,Nakamura, Masaharu

, (2019)

A one-pot synthesis of various 5,10-diaryl-5,10-dihydrophenazines (DADHPs) from diarylamines has been achieved by using an iron-catalyzed C-F amination. Homodimerization of magnesium diarylamides, followed by defluorinative intramolecular cyclization (dou

Ligand-Free Iron-Catalyzed C-F Amination of Diarylamines: A One-Pot Regioselective Synthesis of Diaryl Dihydrophenazines

Aoki, Yuma,O'Brien, Harry M.,Kawasaki, Hiroto,Takaya, Hikaru,Nakamura, Masaharu

supporting information, p. 461 - 464 (2019/01/23)

A one-pot synthesis of various 5,10-diaryl-5,10-dihydrophenazines (DADHPs) from diarylamines has been achieved by using an iron-catalyzed C-F amination. Homodimerization of magnesium diarylamides, followed by defluorinative intramolecular cyclization (dou

Stable nickel(0) phosphites as catalysts for C-N cross-coupling reactions

Kampmann, Sven S.,Sobolev, Alexandre N.,Koutsantonis, George A.,Stewart, Scott G.

supporting information, p. 1967 - 1973 (2014/07/07)

Herein we describe the design and preparation of inexpensive, air-stable nickel phosphite-based catalysts for use in the C-N cross-coupling reaction. The combination of nickel tetrakis(triphenyl phosphite) {Ni[P(OPh) 3]4} and 1,1'-bis(diphenylphosphino)ferrocene (dppf), and in particular a newly developed catalyst (dppf)Ni[P(OPh)3] 2, were found to be extremely effective in catalyzing a range of amination reactions of anilines and amines with aryl chlorides. This new catalyst system offers an alternative to the bis(cyclooctadienyl)nickel [Ni(COD)2] and palladium(0) catalysts commonly used for C-N bond formation.

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