16431-48-4

Basic information

• Product Name: N-ethyl-2-[(E)-2H-pyrrol-2-ylidenemethyl]hydrazinecarbothioamide
• CAS NO: 16431-48-4
• Molecular Formula: C₈H₁₂N₄S
• Molecular Weight: 196.2727
• Mol File: 16431-48-4.mol
• Article Data: 1

Chemical Properties

• Boiling Point: 288.5°C at 760 mmHg
• Flash Point: 128.3°C
• Density: 1.23g/cm³
• Vapor Pressure: 0.00233mmHg at 25°C
• Refractive Index: 1.622
• CAS DataBase Reference: N-ethyl-2-[(E)-2H-pyrrol-2-ylidenemethyl]hydrazinecarbothioamide(CAS DataBase Reference)
• NIST Chemistry Reference: N-ethyl-2-[(E)-2H-pyrrol-2-ylidenemethyl]hydrazinecarbothioamide(16431-48-4)
• EPA Substance Registry System: N-ethyl-2-[(E)-2H-pyrrol-2-ylidenemethyl]hydrazinecarbothioamide(16431-48-4)

Safety Data

• Hazardous Substances Data: 16431-48-4(Hazardous Substances Data)

Upstream product

• 1003-29-8 2-pyrrole aldehyde 
• 13431-34-0 N-ethylthiosemicarbazide 

Relevant articles and documents

A new thio-Schiff base fluorophore with copper ion sensing, DNA binding and nuclease activity

Copper ion recognition and DNA interaction of a newly synthesized fluorescent Schiff base (HPyETSC) were investigated using UV-vis and fluorescent spectroscopy. Examination using these two techniques revealed that the detection of copper by HPyETSC is highly sensitive and selective, with a detection limit of 0.39 μm and the mode of interaction between HPyETSC and DNA is electrostatic, with a binding constant of 8.97 × 104 M-1. Furthermore, gel electrophoresis studies showed that HPyETSC exhibited nuclease activity through oxidative pathway.