1643385-82-3

Basic information

• Product Name: 4-(4-bromophenyl)-1-(3-methylbenzyl)-1H-1,2,3-triazole
• Synonyms: 4-(4-bromophenyl)-1-(3-methylbenzyl)-1H-1,2,3-triazole
• CAS NO: 1643385-82-3
• Molecular Weight: 328.211
• Mol File: 1643385-82-3.mol

Chemical Properties

• CAS DataBase Reference: 4-(4-bromophenyl)-1-(3-methylbenzyl)-1H-1,2,3-triazole(CAS DataBase Reference)
• NIST Chemistry Reference: 4-(4-bromophenyl)-1-(3-methylbenzyl)-1H-1,2,3-triazole(1643385-82-3)
• EPA Substance Registry System: 4-(4-bromophenyl)-1-(3-methylbenzyl)-1H-1,2,3-triazole(1643385-82-3)

Safety Data

• Hazardous Substances Data: 1643385-82-3(Hazardous Substances Data)

Upstream product

• 126799-82-4 1-(azidomethyl)-3-methylbenzene 
• 75230-51-2 4-bromoacetophenone tosylhydrazone 
• 766-96-1 4-bromo-1-ethynylbenzene 
• 620-13-3 1-bromomethyl-3-methyl-benzene 

Relevant articles and documents

An efficient regioselective copper-catalyzed approach to the synthesis of 1,2,3-triazoles from N-tosylhydrazones and azides

An efficient regioselective copper-catalyzed strategy for the synthesis of 1,2,3-triazoles from N-tosylhydrazones and azides has been reported. This transformation opened a new route to synthesize 1,2,3-triazoles which is a common structural motif in natural products and pharmaceuticals. The reactions were smoothly under the optimized conditions and provided the desired product in good yields.

Multicomponent azide-alkyne cycloaddition catalyzed by impregnated bimetallic nickel and copper on magnetite

A new bimetallic catalyst derived from nickel and copper has been used successfully for the first time in the multicomponent reaction of terminal alkynes, sodium azide, and benzyl bromide derivatives. The presence of both metallic species on the surface of magnetite seems to have a positive and synergetic effect. The catalyst loading is the lowest ever published for a catalyst of copper anchored on any type of iron support. The catalyst could be easily removed from the reaction media just by magnetic decantation and it could be reused up to ten times without any negative effect on the initial results. The Royal Society of Chemistry 2014.