164359-99-3Relevant academic research and scientific papers
Regioselective Pd-mediated coupling between 2,6-dichloropurines and organometallic reagents
Gundersen, Lise-Lotte,Langli, Geir,Rise, Frode
, p. 1945 - 1948 (1995)
Selective coupling in the purine 6-position has been achieved, by reacting N-benzylated 2,6-dichloropurines with organotin and organozinc reagents. The positional identity of the products were established from long range HETCOR or nOe NMR experiments.
Regiochemistry in Stille couplings of 2,6-dihalopurines
Langli, Geir,Gundersen, Lise-Lotte,Rise, Frode
, p. 5625 - 5638 (1996)
The regiochemistry in Stille couplings of 2,6-dihalopurines have been studied. 2,6-Dichloropurines react selectively in the 6-position, and 6-chloro-2-iodopurines and 2-bromo-6-chloropurines in the 2-position.
