1643654-92-5

Basic information

• Product Name: (S)-1-morpholino-2-((S)-2-nitro-1-phenylethyl)butane-1,3-dione
• Synonyms: (S)-1-morpholino-2-((S)-2-nitro-1-phenylethyl)butane-1,3-dione
• CAS NO: 1643654-92-5
• Molecular Weight: 320.345
• Mol File: 1643654-92-5.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (S)-1-morpholino-2-((S)-2-nitro-1-phenylethyl)butane-1,3-dione(CAS DataBase Reference)
• NIST Chemistry Reference: (S)-1-morpholino-2-((S)-2-nitro-1-phenylethyl)butane-1,3-dione(1643654-92-5)
• EPA Substance Registry System: (S)-1-morpholino-2-((S)-2-nitro-1-phenylethyl)butane-1,3-dione(1643654-92-5)

Safety Data

• Hazardous Substances Data: 1643654-92-5(Hazardous Substances Data)

Upstream product

• 5153-67-3 nitrostyrene 
• 16695-54-8 1-(morpholin-4-yl)butane-1,3-dione 

Relevant articles and documents

Organocatalytic enantio- and diastereoselective conjugate addition to nitroolefins: When ketoamides surpass ketoesters

Our findings on the bifunctional squaramide-catalyzed enantioselective conjugate addition of ketoamides to nitroolefins are disclosed. It appears that simple acyclic methylene ketoamides, unlike the extensively studied ketoesters, afford the products in excellent diastereoselectivities, and maintain high yields and enantioselectivities. Moreover, competition and kinetic studies were conducted to rationalize the observed reactivity and selectivity. The high level of diastereocontrol, along with the amenability of the amide group to postfunctionalization, dramatically increase the synthetic usefulness of the transformation.