1643966-26-0

Basic information

• Product Name: bis[2-(diphenylphosphanyl)-6-methylphenyl] (2R,3R,5R,6R)-5,6-dimethoxy-5,6-dimethyl-1,4-dioxane-2,3-dicarboxylate
• Synonyms: bis[2-(diphenylphosphanyl)-6-methylphenyl] (2R,3R,5R,6R)-5,6-dimethoxy-5,6-dimethyl-1,4-dioxane-2,3-dicarboxylate
• CAS NO: 1643966-26-0
• Molecular Weight: 812.836
• Mol File: 1643966-26-0.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: bis[2-(diphenylphosphanyl)-6-methylphenyl] (2R,3R,5R,6R)-5,6-dimethoxy-5,6-dimethyl-1,4-dioxane-2,3-dicarboxylate(CAS DataBase Reference)
• NIST Chemistry Reference: bis[2-(diphenylphosphanyl)-6-methylphenyl] (2R,3R,5R,6R)-5,6-dimethoxy-5,6-dimethyl-1,4-dioxane-2,3-dicarboxylate(1643966-26-0)
• EPA Substance Registry System: bis[2-(diphenylphosphanyl)-6-methylphenyl] (2R,3R,5R,6R)-5,6-dimethoxy-5,6-dimethyl-1,4-dioxane-2,3-dicarboxylate(1643966-26-0)

Safety Data

• Hazardous Substances Data: 1643966-26-0(Hazardous Substances Data)

Upstream product

• 181586-74-3 (2R,3R,5R,6R)-5,6-dimethoxy-5,6-dimethyl[1,4]dioxane-2,3-dicarboxylic acid dimethyl ester 
• 1158430-65-9 C₁₉H₁₉BBrOP 
• 13319-71-6 2-bromo-6-methylphenol 
• 95-48-7 ortho-cresol 
• 1158430-25-1 2-boranatodiphenylphosphanyl-6-methylphenol 
• 1643965-98-3 (2R,3R,5R,6R)-5,6-dimethoxy-5,6-dimethyl-1,4-dioxane-2,3-dicarboxyl dichloride 

Relevant articles and documents

Synthesis of C2-symmetric bisphosphine ligands from tartaric acid, and their performance in the Pd-Catalyzed asymmetric o-allylation of a phenol

Starting from tartaric acid derived chiral diols or dicarboxylic acid dichlorides with either a 2,2-dimethyl-1,3-dioxolane (Taddol) or a 2,3-dimethoxy-2,3-dimethyl-1,4-dioxane (Tatrol) core structure, and BH 3-protected ortho-phosphanyl phenols, a set of fourteen new C 2-symmetric diphosphine ligands was synthesized. In addition, three related ligands were obtained from ortho-diphenylphosphino-anilines. The fully characterized ligands were then tested in the Pd-catalyzed enantioselective O-allylation of 4-methoxyphenol using crotyl methyl carbonate as a reagent. In addition, a pseudo-intramolecular variant of the reaction, using crotyl 4-methoxyphenyl carbonate as a substrate, was studied. The so-called Trost ligand was used as a reference. Although the Trost ligand (3 mol-%) gave up to 84% ee, one of the new ligands showed higher activity (50% ee with 0.075 mol-%). Copyright