1644-22-0Relevant academic research and scientific papers
Processes for preparing pentafluoroethoxy- and pentafluoroethylthiobenzene drivatives
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, (2008/06/13)
A process for the preparation of (pentafluoroethoxy)- and (pentafluoroethylthio)benzene derivatives either from phenol, thiophenol or from halobenzene. A halobenzene is reacted with trifluoroethanol or a phenol or a thiophenol is reacted with a compound of the formula CF3 --CH2 --O--R'. The product is chlorinated and the chlorinated product is fluorinated in liquid hydrofluoric acid in the presence of a Lewis acid. The compounds obtained by the process of the present invention are used as synthesis intermediates in the phytosanitary, pharmaceutical and veterinary industries, and are used in lubricants.
Process for the preparation of α, α-difluoroalkyl phenyl ether derivatives
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, (2008/06/13)
The present invention relates to a novel process for the preparation of an α,α-difluoroalkyl phenyl ether of formula I STR1 wherein R1 is hydrogen, halogen, amino, nitro, --SO2 --R4, --S--R5, --SO--R6
Process for the preparation of compounds containing a difluoromethylene or trifluoromethyl group
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, (2008/06/13)
A process for the preparation of compounds containing a difluoromethylene or trifluoromethyl group. A compound containing a carbonyl group, preferbly an acid, acid halide, amide, ketone or any compound containing a perhaloalkylcarbonyl moiety is placed, in anhydrous liquid hydrofluoric acid, in contact with boron trifluoride in a quantity such that the absolute pressure of boron trifluoride in the reaction system is at least one bar for a time sufficient to convert the carbonyl group to a difluormethylene or trifluoromethyl group. The compounds obtained are useful as synthesis intermediates in the pharmaceutical, plant-protection and dye industries, as anesthetics or as heat-transfer and lubricating fluids.
Process for preparing compounds containing a difluoromethylene group in a position α to an oxygen atom
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, (2008/06/13)
A process for the preparation of compounds containing a difluoromethylene group in a position α to an oxygen atom. An alcohol or a phenol is brought into contact with trifluoroacetic acid or a halide or anhydride thereof in anhydrous liquid hydrofluoric acid, in the presence of boron trifluoride, in a quantity such that the absolute pressure of boron trifluoride is at least about one bar. The compounds obtained according to the invention are used as synthesis intermediates in the pharmaceutical, plant-protection, and dye industries, as anesthetics and as additives for lubricating oils.
