1644077-19-9Relevant academic research and scientific papers
Copper(I) bromide-catalyzed carbonylative coupling of aryl halides with phenols, alcohols and amines using sodium cyanide as C1 source: A synthesis of carboxylic acid derivatives
Prasad, Pragati K,Sudalai, Arumugam
, p. 2231 - 2238 (2014)
A new carbon monoxide-free synthesis of carboxylate derivatives via carbonylative coupling of aryl bromides with phenols, alcohols, amines and acids in the presence of copper(I) bromide as catalyst and sodium cyanide in a stoichiometric amount has been developed. Its intramolecular version provides for the preparation of lactones (e.g., isochroman-1-ones and isobenzfuranones), imides, anhydrides and lactams in excellent yields (73-96%).
