1644085-81-3

Basic information

• Product Name: 1-(2,4-dimethylphenyl)-4,4,4-trifluoro-3-hydroxybutan-1-one
• CAS NO: 1644085-81-3
• Molecular Weight: 246.229
• Mol File: 1644085-81-3.mol

Chemical Properties

• CAS DataBase Reference: 1-(2,4-dimethylphenyl)-4,4,4-trifluoro-3-hydroxybutan-1-one(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(2,4-dimethylphenyl)-4,4,4-trifluoro-3-hydroxybutan-1-one(1644085-81-3)
• EPA Substance Registry System: 1-(2,4-dimethylphenyl)-4,4,4-trifluoro-3-hydroxybutan-1-one(1644085-81-3)

Safety Data

• Hazardous Substances Data: 1644085-81-3(Hazardous Substances Data)

Upstream product

• 1000556-81-9 C₁₁H₁₂O₃ 

Relevant articles and documents

Copper-catalyzed one-pot denitrogenative-dehydrogenative-decarboxylative coupling of β-ketoacids with trifluorodiazoethane: Facile access to trifluoromethylated aldol products

A novel copper-catalyzed one-pot cross-coupling of β-ketoacids with in situ generated trifluorodiazoethane has been developed. This reaction provides a direct and efficient method, in which one C-C bond and one C-O bond were formed in a carbenoid center with concomitant denitrogenation-dehydrogenation- decarboxylation, to afford trifluoromethylated aldol products. In several preliminary experiments, good to high enantioselectivities were also obtained.