1644448-45-2Relevant academic research and scientific papers
Access to oxoquinoline heterocycles by N-heterocyclic carbene catalyzed ester activation for selective reaction with an enone
Fu, Zhenqian,Jiang, Ke,Zhu, Tingshun,Torres, Jaume,Chi, Yonggui Robin
, p. 6506 - 6510 (2014/06/24)
Organocatalytic ester activation is developed for a highly selective cascade reaction between saturated esters and amino enones. The reaction involves activation of the β-carbon atom of the ester as a key step. This method allows a single-step access to multicyclic oxoquinoline-type heterocycles with high enantiomeric ratios.
