1644540-87-3Relevant academic research and scientific papers
Hypervalent iodine(III) promoted direct synthesis of imidazo[1,2-a] pyrimidines
Qian, Guangyin,Liu, Bingxin,Tan, Qitao,Zhang, Siwen,Xu, Bin
, p. 4837 - 4843 (2014/08/05)
An efficient and mild synthesis of imidazo[1,2-a]pyrimidine derivatives has been developed from readily available pyrimidyl arylamines or enamines through a hypervalent iodine-promoted intramolecular C-H bond cycloamination reaction. This protocol allows for the facile construction of biologically active bicyclic imidazo[1,2-a]pyrimidine skeletons as well as other imidazo[1,2-a]-type fused heterocycles.
