1644541-30-9Relevant academic research and scientific papers
Total synthesis of blennolide mycotoxins: Design, synthetic routes and completion
Meister, Anne C.,Encinas, Arantxa,Sahin, Huelya,Singer, Emilie M. C.,Nising, Carl F.,Nieger, Martin,Braese, Stefan
, p. 4861 - 4875 (2014)
Mycotoxins of the tetrahydroxanthone class of natural products possess a large number of interesting biological properties. In this full paper, we present our synthetic strategy to some members of this class of compounds, namely the blennolides A and C. We disclose the scope and limitations of the functionalization of various xanthones derived from a domino oxa-Michael-aldol condensation and pursue dimerization of these xanthones. Furthermore, the first crystal structure of blennolide C has been obtained.
