164471-64-1

Basic information

• Product Name: 2-(4-trimethylsilyl-1,3-butadiyn-1-yl)aniline
• Synonyms: 2-(4-trimethylsilyl-1,3-butadiyn-1-yl)aniline
• CAS NO: 164471-64-1
• Molecular Weight: 213.354
• Mol File: 164471-64-1.mol
• Article Data: 5

Chemical Properties

• CAS DataBase Reference: 2-(4-trimethylsilyl-1,3-butadiyn-1-yl)aniline(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(4-trimethylsilyl-1,3-butadiyn-1-yl)aniline(164471-64-1)
• EPA Substance Registry System: 2-(4-trimethylsilyl-1,3-butadiyn-1-yl)aniline(164471-64-1)

Safety Data

• Hazardous Substances Data: 164471-64-1(Hazardous Substances Data)

Upstream product

• 4526-07-2 1,4-bis(trimethylsilyl)-1,3-butadiyne 
• 615-43-0 2-iodophenylamine 
• 4526-06-1 trimethylsilyl-1,3-butadiyne 
• 52670-38-9 2-ethynylaniline 
• 1066-54-2 trimethylsilylacetylene 

Downstream Products

• 1436750-30-9 1-(2,2,2-trichloroacteyl)-3-{2-[4-(trimethylsilyl)buta-1,3-diynyl]phenyl}urea 
• 1436751-69-7 1,2-dihydro-1-methylene-2-phenylimidazo[1,5-a]indol-3-one 
• 1436751-59-5 2,3-diphenylpyrimido[1,6-a]indol-1(2H)-one 
• 1436751-45-9 3-phenylpyrimido[1,6-a]indol-1(2H)-one 
• 1436751-04-0 1-phenyl-3-[2-(phenylbuta-1,3-diyn-1-yl)phenyl]urea 
• 1436750-99-0 1-[2-(buta-1,3-diynyl)phenyl]-3-phenylurea 
• 1436750-94-5 1-[2-(buta-1,3-diynyl)phenyl]-3-methylurea 
• 1436750-78-5 1-{2-[4-(trimethylsilyl)buta-1,3-diynyl]phenyl}urea 
• 1436750-74-1 1-[2-(phenylbuta-1,3-diynyl)phenyl]urea 
• 1436750-13-8 1-(2-buta-1,3-diynyl)phenylurea 
• 1436751-74-4 2-ethynyl-1H-indole-1-carboxamide 
• 1043252-33-0 2-[4-(4-aminophenyl)buta-1,3-diyn-1-yl]aniline 
• 1043252-35-2 2-[4-(4-methoxyphenyl)buta-1,3-diyn-1-yl]aniline 
• 1043252-32-9 2-[4-(naphthalen-1-yl)buta-1,3-diyn-1-yl]aniline 

Relevant articles and documents

Copper-catalyzed tandem reaction between imines and alcohols leading to indoles

A copper-catalyzed tandem reaction between 2-alkynyl-N-arylideneanilines and alcohols is found to produce N-(alkoxybenzyl)indoles in good to high yields. A wide variety of substituted N-(alkoxybenzyl)indole derivatives can be synthesized by utilizing this

Selectivity for Alkynyl or Allenyl Imidamides and Imidates in Copper-Catalyzed Reactions of Terminal 1,3-Diynes and Azides

Copper-catalyzed reactions of terminal 1,3-diynes with electron-deficient azides to generate either 3-alkynyl or 2,3-dienyl imidamides and imidates are described. The selectivity depends on the diyne substituents and the nucleophile that reacts with the ketenimide intermediate generated from the corresponding triazole precursor. Reactions of 1,3-diynes containing a propargylic acetate afford [3]cumulenyl imidamides, while reactions using methanol as the trapping agent selectively generate 2,3-dienyl imidates. Five-membered heterocycles were obtained from 1,3-diynes containing a homopropargylic hydroxyl or amine substituent.

Synthesis of Isocoumarins from o-Iodobenzoic Acid and Terminal Acetylenes Mediated by Palladium Complexes and Zinc Chloride

o-Iodobenzoic acid (1) reacts with various terminal acetylenes (HCCR) in the presence of Pd(PPh3)4, Et3N, and ZnCl2 in DMF to give the corresponding 3-substituted isocoumarins (: R = n-C4H9 (2a); n-C3H7 (3a); CH2OCH3 (4a); C(CH3)2OH (5a); CH2OH (