164514-17-4Relevant articles and documents
Adenosine Kinase Inhibitors. 3. Synthesis, SAR, and Antiinflammatory Activity of a Series of L-Lyxofuranosyl Nucleosides
Ugarkar, Bheemarao G.,Castellino, Angelo J.,DaRe, Jay S.,Ramirez-Weinhouse, Michele,Kopcho, Joseph J.,Rosengren, Sanna,Erion, Mark D.
, p. 4750 - 4760 (2007/10/03)
Chronic inflammatory diseases, such as arthritis and rheumatoid arthritis, remain major health problems worldwide. We previously demonstrated that adenosine kinase inhibitors (AKIs) exhibit antiinflammatory effects by inhibiting TNF-α production, neutroph