164517-88-8Relevant articles and documents
Studies on the Synthesis and Biological Activity of Certain Spiro Heterocyclic Compounds
Khalafallah, A.K.,Koraiem, A.I.,El-Maghraby, M.A.,Shindy, H.A.
, p. 159 - 166 (2007/10/02)
A series of some spiro compounds covering thiazolidinones, β-lactams and triazolidine incorporating piperidino (2,3-g)1,2,3,4,6,7,8,9-octahydroquinolinoquinone (IIIa-c,IVa-c and Va-c) were prepared.The synthesis was proceeded through cycloaddition reaction of thioglycolic acid, monochloroacetyl chloride and diazomethane to the newly reported bis aryl (napththyl) iminopiperidinoc (2,3-9)-1,2,3,4,6,7,8,,9-octahydro-quinolinoquinone (1a-c).The biological screening of some selected spiro compounds was tested against some bacterial and fungal strains.