1645294-11-6

Basic information

• Product Name: 2-(3-(4-methoxyphenyl)prop-1-yn-1-yl) aniline
• Synonyms: 2-(3-(4-methoxyphenyl)prop-1-yn-1-yl) aniline
• CAS NO: 1645294-11-6
• Molecular Weight: 237.301
• Mol File: 1645294-11-6.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 2-(3-(4-methoxyphenyl)prop-1-yn-1-yl) aniline(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(3-(4-methoxyphenyl)prop-1-yn-1-yl) aniline(1645294-11-6)
• EPA Substance Registry System: 2-(3-(4-methoxyphenyl)prop-1-yn-1-yl) aniline(1645294-11-6)

Safety Data

• Hazardous Substances Data: 1645294-11-6(Hazardous Substances Data)

Upstream product

• 13540-76-6 3-(4-methoxyphenyl)prop-1-yne 
• 615-43-0 2-iodophenylamine 

Downstream Products

• 1632137-71-3 8-methoxy-5-tosyl-5H-benzo[b]carbazole 
• 1632137-96-2 C₃₁H₃₁NO₇S 
• 1632138-08-9 C₂₄H₂₅NO₅ 

Relevant articles and documents

Gold-catalyzed tandem reaction of 2-alkynylanilines followed by 1,6-conjugate addition to: P -quinone methides: Efficient access to unsymmetrical diarylindolylmethanes

A simple, mild, efficient and chemoselective catalytic method for the straightforward synthesis of an interesting class of 2-aryl/alkyl-substituted-3-diaryl indolyl methanes in high yield is reported. This atom-efficient method proceeds via a gold-catalyzed one-pot sequential intramolecular hydroamination (C-N bond formation) of 2-alkynylanilines followed by a 1,6-conjugate addition to p-quinonemethides. The p-quinonemethides, which contain aldehyde functional groups, preferentially participate in 1,6-conjugate addition, while the aldehyde functional group remains unreactive.