164531-22-0Relevant academic research and scientific papers
Highly efficient and stereoselective N-vinylation of oxiranecarboxamides and unprecedented 8-endo-epoxy-arene cyclization: Expedient and biomimetic synthesis of some clausena alkaloids
Yang, Luo,Deng, Gang,Wang, De-Xian,Huang, Zhi-Tang,Zhu, Jie-Ping,Wang, Mei-Xiang
, p. 1387 - 1390 (2007/10/03)
Figure presented Catalyzed by Cul/N,N-dimethylglycine, oxiranecarboxamides underwent a highly efficient and stereoselective N-vinylation reaction with (Z)-1-aryl-2-bromoethenes to afford the corresponding enamides. The method has been applied to a straigh
The Total Synthesis of (+)-Hapalindole Q by an Organomediated Diels-Alder Reaction
Kinsman, Aaron C.,Kerr, Michael A.
, p. 14120 - 14125 (2007/10/03)
The total synthesis of (+)-hapalindole Q has been achieved. The key step is a Diels-Alder reaction mediated by MacMillan's organocatalyst to provide the critical intermediate with high enantiose-lectivity (93% ee). This step establishes the proper arrange
Synthesis and serotonin receptor affinities of a series of trans-2- (indol-3-yl)cyclopropylamine derivatives
Vangveravong, Suwanna,Kanthasamy, Arthi,Lucaites, Virginia L.,Nelson, David L.,Nichols, David E.
, p. 4995 - 5001 (2007/10/03)
A series of four racemic ring-substituted trans-2-(indol-3- yl)cyclopropylamine derivatives was synthesized and tested for affinity at the 5-HT(1A) receptor, by competition with [3H]-8-OH-DPAT in rat hippocampal homogenates, and for affinity at
Stereoselective Synthesis of trans-2-(Indol-3-yl)cyclopropylamines: Rigid Tryptamine Analogues
Vangveravong, Suwanna,Nichols, David E.
, p. 3409 - 3413 (2007/10/02)
A procedure for the preparation of trans-2-(indol-3-yl)cyclopropylamines is reported.The key step in the sequence is a stereoselective palladium-catalyzed cyclopropanation of the indole-3-acryloyl derivative of Oppolzer's chiral sultam (bornanesulta
