164642-21-1 Usage
Description
N-[1-(aminomethyl)cyclopentyl]-N,N-dimethylamine is an organic amine with the molecular formula C10H22N2. It features a cyclopentyl group and two methyl groups, making it a highly reactive compound capable of forming strong covalent bonds with other molecules. This versatility positions it as a valuable building block in organic chemistry and a common reagent in organic synthesis and pharmaceutical manufacturing.
Uses
Used in Organic Synthesis:
N-[1-(aminomethyl)cyclopentyl]-N,N-dimethylamine is used as a reagent for its ability to participate in various chemical reactions, facilitating the formation of new compounds and contributing to the advancement of organic chemistry.
Used in Pharmaceutical Manufacturing:
In the pharmaceutical industry, N-[1-(aminomethyl)cyclopentyl]-N,N-dimethylamine serves as a precursor in the production of various drugs, leveraging its reactivity to create medicinally relevant molecules.
Used in Research Applications:
Due to its unique molecular structure and properties, N-[1-(aminomethyl)cyclopentyl]-N,N-dimethylamine is also utilized in research settings to explore new chemical pathways and develop innovative applications in science and medicine.
Check Digit Verification of cas no
The CAS Registry Mumber 164642-21-1 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,6,4,6,4 and 2 respectively; the second part has 2 digits, 2 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 164642-21:
(8*1)+(7*6)+(6*4)+(5*6)+(4*4)+(3*2)+(2*2)+(1*1)=131
131 % 10 = 1
So 164642-21-1 is a valid CAS Registry Number.
InChI:InChI=1/C8H18N2/c1-10(2)8(7-9)5-3-4-6-8/h3-7,9H2,1-2H3
164642-21-1Relevant articles and documents
Radiosynthesis of 3-(3-[18F]fluoropropoxy)-4-(benzyloxy)-N-[(1- dimethylaminocyclopentyl)methyl]-5-methoxybenzamide, a potential PET radiotracer for the glycine transporter GlyT-2
Tian, Haibin,Vogel, Rebecca,Amici, Louis,Tamagnan, Gilles,Baldwin, Ronald M.
, p. 1247 - 1258 (2007/10/03)
The recently described selective and potent GlyT2 antagonist, 4-benzyloxy-3, 5-dimethoxy-N-[(1-dimethylaminocyclopentyl) methyl]benzamide (IC50 = 16 nM) provided an important additional tool to further characterize GlyT2 pharmacology. In order to identify an effective PET radioligand for in vivo assessment of the GlyT-2 transporter, 3-(3-[ 18F]fluoropropoxy)-4-(benzyloxy)-N-((1-dimethylaminocyclopentyl) methyl)-5-methoxybenzamide ([18F]3), a novel analog of 4-benzyloxy-3,5-dimethoxy-N-[(1-dimethylaminocyclopentyl) methyl]benzamide was synthesized using a one-pot, two-step method. The NCA radiofluorination of 1,3-propanediol di-p-tosylate in the presence of K2CO3 and Kryptofix-222 in acetonitrile gave 81% 3-[18F]fluoropropyl tosylate, which was subsequently coupled with 4-benzyloxy-3-hydroxy-5-methoxy-N-[(1- dimethylaminocyclopentyl) methyl]-benzamide in the same reaction vessel. Solvent extraction and HPLC (Eclipse XDB-C8 column, 80/20/0.1 MeOH/H 2O/Et3N, 3.0 ml/min) gave [18F]3 in 98.5% radiochemical purity. The radiochemical yield was determined to be 14.0-16.2% at EOS, and the specific activity was 1462 ± 342 GBq/μmol. The time of synthesis and purification was 128 min. The final product was prepared as a sterile saline solution suitable for in vivo use. Copyright
