164653-60-5 Usage
Uses
Used in Pharmaceutical Industry:
1,2,3,4-Tetrahydro-5-isoquinolinol Acetate is used as a key intermediate in the preparation of pyridopyrimidines, which are therapeutic modulators of GPR119 activity. This makes it a valuable compound for the development of new drugs targeting metabolic disorders, such as type 2 diabetes and obesity, by modulating the GPR119 receptor.
Check Digit Verification of cas no
The CAS Registry Mumber 164653-60-5 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,6,4,6,5 and 3 respectively; the second part has 2 digits, 6 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 164653-60:
(8*1)+(7*6)+(6*4)+(5*6)+(4*5)+(3*3)+(2*6)+(1*0)=145
145 % 10 = 5
So 164653-60-5 is a valid CAS Registry Number.
164653-60-5Relevant academic research and scientific papers
COMPOUNDS AND COMPOSITIONS AS MODULATORS OF GPR119 ACTIVITY
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Page/Page column 65-66, (2009/10/18)
The invention provides compounds of Formula (I): pharmaceutical compositions comprising such compounds and methods of using such compounds to treat or prevent diseases or disorders associated with the activity of GPR119.
TETRAHYDROISOQUINOLINES AS ALPHA-2 ANTAGONISTS AND BIOGENIC AMINE UPTAKE INHIBITORS
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, (2008/06/13)
The present invention provides a tetrahydroisoquinoline compound of the formula STR1 or a pharmaceutically acceptable salt thereof which is an antagonist for alpha-2 adrenoreceptors and/or which inhibits biogenic amine uptake.
