16466-97-0Relevant articles and documents
Palladium(II)-catalyzed dicarboxymethylation of chiral allylic alcohols: Chirality transfer affording optically active diesters containing three contiguous chiral centers
Hamed, Othman,Henry, Patrick M.,Becker, Daniel P.
supporting information; experimental part, p. 3514 - 3517 (2010/09/05)
This manuscript describes the extension of Stille's palladium-catalyzed olefin dicarbonylation reaction to chiral allylic alcohols with chirality transfer to afford the corresponding chiral alcohol functionalized with bis-carbomethoxy esters, containing three contiguous chiral centers, in good to excellent diastereoselectivities (78-98%).
Poly(dimethylsilmethylene) methylacetylene compound and a method for the preparation thereof
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, (2008/06/13)
The invention provides a novel organosilicon compound poly(dimethylsilmethylene) methylacetylene compound of the formula MeC C--SiMe2 --CH2 --SiMe2)n Me, in which Me is a methyl group and n is a positive integer of 1 to 25. The compound is synthesized by reacting a propynylmagnesium halide of the formula MeC CMgX, in which X is a halogen atom, or (propynyl dimethylsilyl)methylmagnesium chloride of the formula MeC C--SiMe2 --CH2 MgCl with chloromethyl dimethyl chlorosilane in the presence of metallic magnesium and hydrolyzing the reaction product. Specifically, 1-propynyl-1,1,3,3,3-pentamethyl disilmethylene, i.e. the inventive compound with n=1, is synthesized by reacting (propynyl dimethylsilyl)methylmagnesium chloride with trimethyl chlorosilane.