164738-24-3

Downstream Products

• 164738-25-4 (4-Methoxy-phenyl)-[(1R,7S)-3-(toluene-4-sulfonyl)-3,8-diaza-bicyclo[5.1.0]oct-8-yl]-methanone 
• 189013-31-8 (4-Benzyloxy-phenyl)-[(1R,7S)-3-(toluene-4-sulfonyl)-3,8-diaza-bicyclo[5.1.0]oct-8-yl]-methanone 
• 1054605-20-7 3,5-Bis-benzyloxy-4-(2-benzyloxy-6-benzyloxycarbonyl-benzoyl)-benzoic acid (3R,4R)-3-(4-benzyloxy-benzoylamino)-1-(toluene-4-sulfonyl)-azepan-4-yl ester 
• 189013-34-1 3,5-Bis-benzyloxy-4-(2-benzyloxy-6-benzyloxycarbonyl-benzoyl)-benzoic acid (3R,4R)-3-(4-benzyloxy-benzoylamino)-azepan-4-yl ester 
• 189013-33-0 (3R,4R)-4-benzyloxy-N-[4-hydroxy-1-(toluene-4-sulfonyl)-azepan-3-yl]-benzamide 

Relevant academic research and scientific papers

The use of vinyl sulfonium salts in the stereo-controlled asymmetric synthesis of epoxide- and aziridine-fused heterocycles: Application to the synthesis of (-)-balanol

(Chemical Equation Presented) Lift your ylides: An asymmetric, epoxy-annulation reaction mediated by a vinyl sulfonium salt converts aminoaldehydes and -ketones into fused heterocyclic epoxides. The methodology was extended to an aziridine-annulation reac

Total Synhesis of Balanol, Part 1. Enantioselective Synthesis of the Hexahydroazepine Ring via Chiral Epoxides and Azidirines

Three differents routes to the hexahydroazepine unit of the natural products balanol (1) and ophicordin (2) are described.The common starting material is the chiral epoxy alcohol 3 which is converted to the balanol degradation product 10 (Scheme 1) or to