164789-52-0

Upstream product

• 163768-66-9 2,8-dioxaspiro<4.5>decane-1,3,7,9-tetrone 
• 62-53-3 aniline 
• 133880-45-2 3-carboxy-3-(carboxymethyl)pentanedioic acid 
• 86902-89-8 methyl 1-(methoxycarbonyl)-4-methyl-3-cyclohexene-1-acetate 
• 232258-41-2 1-carboxy-4-methyl-3-cyclohexene-1-acetic acid 
• 163768-67-0 8-methyl-2-oxaspiro<4.5>dec-7-ene-1,3-dione 

Relevant academic research and scientific papers

Synthesis of 2,8-dioxaspiro[4.5]decane-1,3,7,9-tetrone and the Reactions with amines

For the studies of highly-sophisticated utilization of itaconic anhydride, some compounds of polybasic carboxylic acids having a quaternary or a spiro carbon atom were prepared, starting from itaconic anhydride and isoprene. Aliphatic tetracarboxylic dianhydride having a spiro carbon atom with five- and six-membered rings, 2,8-dioxaspiro[4.5]decane-1,3, 7,9- tetrone (TCDA), was also obtained. The reaction of TCDA with primary amines and subsequent dehydration gave two types of products, either diimides or imide (with five-membered ring)-anhydrides (with six-membered ring), depending on the hydrocarbon moiety of the amines used. It was suggested that each imide-anhydride was formed by the intramolecular ring transformation of the intermediate amic acid-anhydride.