164906-64-3

Usage

Uses

Used in Medicinal Chemistry:
(2S,3R)-1-(diphenylmethyl)-3-hydroxy-2-methylazetidine is utilized as a key intermediate in the synthesis of various pharmaceutical compounds due to its unique structure and stereochemistry. Its functional groups and molecular configuration make it a promising candidate for the development of new drugs with potential therapeutic applications.
Used in Organic Synthesis:
In the field of organic chemistry, (2S,3R)-1-(diphenylmethyl)-3-hydroxy-2-methylazetidine serves as a valuable building block for the creation of complex organic molecules. Its specific stereochemistry and functional groups allow for targeted synthesis and the development of novel chemical entities with potential applications in various industries.
Used in Pharmaceutical Research:
(2S,3R)-1-(diphenylmethyl)-3-hydroxy-2-methylazetidine is employed as a subject of study in pharmaceutical research to explore its biological activities and potential therapeutic effects. Its unique structure and stereochemistry make it an interesting target for the investigation of new drug candidates and the advancement of medicinal chemistry.

Upstream product

• 1260757-70-7 (+/-)-trans-1-(diphenylmethyl)-3-hydroxy-2-methylazetidine 
• 1260757-70-7 1-benzhydryl-2-methylazetidin-3-ol 
• 91-00-9 Benzhydrylamine 

Downstream Products

• 164906-66-5 (2S,3R)-1-(diphenylmethyl)-2-methyl-3-(methylsulfonyloxy)azetidine 
• 920282-10-6 (2S,3R)-2-methylazetidin-3-ol 
• 161816-69-9 (2S,3R)-3-amino-1-(diphenylmethyl)-2-methylazetidine 

Relevant academic research and scientific papers

COMPOUNDS USEFUL IN INHIBITING KETOHEXOKINASE AND METHODS OF MAKING AND USING THE SAME

The present invention relates to compounds that can act as inhibitors of ketohexokinase (KHK) and that can be useful in the treatment of diseases and/or disorders associated with KHK. In some embodiments, the present invention relates to compounds and com

Discovery of PF-06835919: A Potent Inhibitor of Ketohexokinase (KHK) for the Treatment of Metabolic Disorders Driven by the Overconsumption of Fructose

Increased fructose consumption and its subsequent metabolism have been implicated in metabolic disorders such as nonalcoholic fatty liver disease and steatohepatitis (NAFLD/NASH) and insulin resistance. Ketohexokinase (KHK) converts fructose to fructose-1

DISUBSTITUTED PYRAZOLE COMPOUNDS

The present invention provides a compound of Formula I or a pharmaceutically acceptable salt thereof, and the use of compounds of Formula I for treating metabolic conditions, such as type 2 diabetes mellitus, heart failure, diabetic kidney disease, and no

Substituted Azetidine compounds, their preparation and use as medicaments

The present invention relates to substituted Azetidine compounds of general formula (I), methods for their preparation, medicaments comprising these compounds as well as their use for the preparation of a medicament for the treatment of humans and animals

7-Azetidinylquinolones as Antibacterial Agents. 3. Synthesis, Properties and Structure-Activity Relationships of the Stereoisomers Containing a 7-(3-Amino-2-methyl-1-azetidinyl) Moiety

A series of stereochemically pure 7-(3-amino-2-methyl-1-azetidinyl)-1,4-dihydro-6-fluoro-4-oxoquinoline- and -1,8-naphthyridine-3-carboxylic acids, with varied substituents at the 1-, 5-, and 8-positions, was prepared to determine the effects of chirality