164913-51-3

Basic information

• Product Name: (4S,5R)-4-methyl-3-<(2R,3S)-2-methyl-3-phenyl-3-(tosylamino)propionyl>-5-phenyloxazolidin-2-one
• Synonyms: (4S,5R)-4-methyl-3-<(2R,3S)-2-methyl-3-phenyl-3-(tosylamino)propionyl>-5-phenyloxazolidin-2-one
• CAS NO: 164913-51-3
• Molecular Weight: 492.596
• Mol File: 164913-51-3.mol

Chemical Properties

• CAS DataBase Reference: (4S,5R)-4-methyl-3-<(2R,3S)-2-methyl-3-phenyl-3-(tosylamino)propionyl>-5-phenyloxazolidin-2-one(CAS DataBase Reference)
• NIST Chemistry Reference: (4S,5R)-4-methyl-3-<(2R,3S)-2-methyl-3-phenyl-3-(tosylamino)propionyl>-5-phenyloxazolidin-2-one(164913-51-3)
• EPA Substance Registry System: (4S,5R)-4-methyl-3-<(2R,3S)-2-methyl-3-phenyl-3-(tosylamino)propionyl>-5-phenyloxazolidin-2-one(164913-51-3)

Safety Data

• Hazardous Substances Data: 164913-51-3(Hazardous Substances Data)

Upstream product

• 51608-60-7 N-(benzylidene)-p-methylbenzenesulfonamide 
• 77877-20-4 (4S,5R)-4-methyl-5-phenyl-3-propionyloxazolidin-2-one 
• 16251-45-9 (4S,5R)-4-methyl-5-phenyl-oxazolidin-2-one 
• 164913-55-7 (3R,4S)-3-methyl-4-phenyl-1-tosylazetidin-2-one 

Downstream Products

• 164913-55-7 (3R,4S)-3-methyl-4-phenyl-1-tosylazetidin-2-one 
• 151214-59-4 (3R,4S)-3-methyl-4-phenylazetidin-2-one 
• 164913-54-6 (2R,3S)-(-)-2-methyl-3-(4-methylphenylsulfonamido)-3-phenylpropanoic acid 

Relevant articles and documents

Diastereoselective addition of imidazolidin-2-one controlled enolates to activated imines

Ephedrine-based imidazolidin-2-one chiral auxiliaries afford good syn stereoselectivity in the addition of their derived titanium enolates with an activated imine system. This provides entry into β-amino acid systems.

Addition to activated imines of enolates from chiral N-acyloxazolidinones

The lithium and titanium enolates of N-acyloxazolidinones 1a-c add in their chelated forms to PhCH=NTs, to give stereoselectively the β-amino acid derivatives 3a-c and 4a-c. The relative configurations of the newly created chiral centres were established