164931-18-4

Upstream product

• 1676-75-1 N-benzyloxycarbonyl-O-t-butyl-L-serine 
• 189132-13-6 [(S)-5-((S)-2-Benzyloxycarbonylamino-3-tert-butoxy-propionylamino)-5-(2-cyclohexyl-ethylcarbamoyl)-pentyl]-carbamic acid tert-butyl ester 

Downstream Products

• 1026800-59-8 [(S)-5-[(S)-3-tert-Butoxy-2-(11-imidazol-1-yl-undecanoylamino)-propionylamino]-5-(2-cyclohexyl-ethylcarbamoyl)-pentyl]-carbamic acid tert-butyl ester 
• 1027586-35-1 [(S)-5-[(S)-3-tert-Butoxy-2-(2-{4-[4-(tert-butoxycarbonylamino-methyl)-phenylethynyl]-phenyl}-acetylamino)-propionylamino]-5-(2-cyclohexyl-ethylcarbamoyl)-pentyl]-carbamic acid tert-butyl ester 
• 1026417-79-7 [(S)-5-((S)-3-tert-Butoxy-2-{2-[4-(5-tert-butoxycarbonylamino-pentyl)-phenyl]-acetylamino}-propionylamino)-5-(2-cyclohexyl-ethylcarbamoyl)-pentyl]-carbamic acid tert-butyl ester 

Relevant academic research and scientific papers

Conformationally constrained [p-(ω-aminoalkyl)phenacetyl]-L-seryl-L- lysyl dipeptide amides as potent peptidomimetic inhibitors of Candida albicans and human myristoyl-CoA:protein N-myristoyl transferase

MyristoylCoA:protein N-myristoyltransferase (NMT) covalently attaches the 14-carbon saturated fatty acid myristate, via an amide bond, to the N- terminal glycine residues of a variety of cellular proteins. Genetic studies have shown that NMT is essential