164934-48-9

Upstream product

• 593-56-6 N-methoxylamine hydrochloride 
• 874-98-6 1-bromomethyl-3-methoxybenzene 

Downstream Products

• 735271-41-7 N-(3-methoxybenzyl)-N-(2-propynyl)-O-methylhydroxylamine 
• 735271-43-9 N-methoxy-N-(4-trimethylsiloxy-4,4-diphenyl-2-butynyl)-(m-methoxybenzyl)amine 
• 735271-42-8 N-(3-methoxybenzyl)-N-(4-hydroxy-4,4-diphenyl-2-butynyl)-O-methylhydroxylamine 

Relevant academic research and scientific papers

Intramolecular catalytic Friedel-Crafts reactions with allenyl cations for the synthesis of quinolines and their analogues

(Equation Presented) This paper describes a novel method to synthesize a quinoline backbone by incorporating allenyl cations into a catalytic intramolecular Friedel-Crafts reaction. The initial products were isomerized and aromatized upon treatment with acid and base, respectively, to give quinolines. The basic concept also proved to be promising for 1-benzazepine, 1-benzazocine, or isoquinoline synthesis.