16495-22-0

Upstream product

• 14618-80-5 (R)-benzyl glycidol 
• 149578-21-2 (S)-4-[(benzyloxy)methyl]-2,2-dioxo-1,3,2-dioxathiolane 
• 190733-33-6 (4S)-4-(benzyloxymethyl)-1,3-dioxa-2-thiolane 2-oxide 
• 56552-80-8 (R)-3-benzyloxy-1,2-propanediol 
• 16495-11-7 1,2-Di-O-p-toluenesulfonyl-D-glycerol 3-O-benzyl ether 
• 10387-40-3 potassium thioacetate 

Relevant academic research and scientific papers

Synthesis and characterization of a new chiral phosphinothiol ligand and its palladium(II) complexes

The chiral ligand (1-diphenylphosphino-3-benzyloxy)propane-2-thiol 3 has been prepared both in racemic and enantiomerically enriched (92% e.e.) form. Addition of 2 equiv. of ligand 3 to a solution of [Pd(PPh3)4] gave the diastereoisomeric bischelate complexes [Pd(phosphinothiolato)2] 4 which exhibit a cis-trans equilibrium in solution. Formation of the diastereoisomeric complexes 4 allows the determination of the enantiomeric purity of ligand 3 by 31P NMR spectroscopy. Addition of 1 equiv. of ligand 3 to a solution of [PdCl2(PPh3)2] gave the enantiomeric complexes [PdCl(phosphinothiolate)(PPh3)] 5, which can be converted to the bischelate complexes 4 by addition of a second equivalent of ligand 3. This process allows the selective preparation of the two diastereoisomeric forms of complex 4.

Applications of Cyclic Sulfates of vic-Diols: Synthesis of Episulfides, Olefins, and Thio Sugars

A new efficient and expeditious one-pot synthesis of thiiranes and olefins from cyclic sulfates of inc-diols is described. Opening of cyclic sulfates with potassium thioacetate or potassium thiocyanate followed by treatment with sodium methoxide led to ep