16495-87-7Relevant academic research and scientific papers
Synthesis of 4-sulfenyl isoxazoles through AlCl3-mediated electrophilic cyclization and sulfenylation of 2-alkyn-1-one O-methyloximes
Gao, Wen-Chao,Cheng, Yu-Fei,Chang, Hong-Hong,Li, Xing,Wei, Wen-Long,Yang, Peng
, p. 4312 - 4317 (2019)
An efficient method for the synthesis of 4-sulfenyl isoxazoles has been developed via AlCl3-mediated electrophilic cyclization/sulfenylation of 2-alkyn-1-one O-methyloximes. Remarkably, N-arylsulfanylsuccinimides are employed as electrophiles for the construction of 4-arylsulfanyl isoxazoles, and 4-alkylsulfanyl isoxazoles are accessed with dialkyl disulfides as electrophiles.
