1649501-89-2Relevant articles and documents
Palladium-Catalyzed C–S Bond Formation of Stable Enamines with Arene/Alkanethiols: Highly Regioselective Synthesis of β-Amino Sulfides
Jiang, Yaojia,Liang, Gaohui,Zhang, Cong,Loh, Teck-Peng
, p. 3326 - 3330 (2016)
A direct and regiocontrolled thiolation method to access β-amino sulfides through the palladium-catalyzed C(sp2)–H functionalization of stable enamines was described. The reaction was realized under mild conditions by adding an external phosphi
Microwave-assisted synthesis of β-amino-α,β-unsaturated esters: a rapid and efficient access to (Z)-methyl 3-amino-2-substituted acrylate
Cao, Han,Liu, Xue-jing,Li, Peng-fei,Bie, Fu-sheng,Shi, Yi-jun,Yan, Peng,Han, Ying
, p. 2160 - 2167 (2021/05/27)
We report a two-step rapid and efficient synthesis of β-amino-α,β-unsaturated esters. Microwave-assisted synthesis was used throughout the process. Seventeen β-amino-α,β-unsaturated esters were produced in excellent yields and short reaction times. The ef
Efficient synthetic approach to substituted benzo[b]furans and benzo[b]thiophenes by iodine-promoted cyclization of enaminones
Labarrios, Ehecatl,Jerezano, Alberto,Jimenez, Fabiola,Del Carmen Cruz, Maria,Delgado, Francisco,Zepeda, L. Gerardo,Tamariz, Joaquin
, p. 954 - 971 (2014/08/05)
An efficient synthetic approach to the substituted benzo[b]furan and benzo[b]thiophene scaffolds by iodine-mediated cyclization of the corresponding enaminones is described. This protocol was applied to a large series of these latter precursors to afford the respective benzoheterocycles substituted at the C-2 position by a carbonyl group functionality. A study of the factors that control this process reveals that the reactivity depends on the presence of electron-donor groups in the aryl ring of the aryloxycarbonylic and arylthiocarbonylic moieties.
