165126-85-2

Upstream product

• 108-91-8 cyclohexylamine 
• 165126-96-5 [(2S,5R)-5-(5,7-Dichloro-imidazo[4,5-b]pyridin-3-yl)-tetrahydro-furan-2-yl]-methanol 
• 165126-97-6 5,7-dichloro-3-(2,3-dideoxy-5-O-p-toluoyl-β-D-glycero-pentofuranosyl)-3H-imidazo<4,5-b>pyridine 
• 24485-01-6 5,7-dichloro-3H-imidazo<4,5-b>pyrimidine 
• 133635-44-6 methyl 2,3-dideoxy-5-O-(4-methylbenzoyl)-D-glycero-pentofuranoside 

Relevant academic research and scientific papers

Inhibitory effects of 1-deazaadenosine analogues on HIV replication and adenosine deaminase

A series of 2',3'-dideoxy-N6-(cyclo)alkyl-1-deazaadenosine derivatives were synthesized starting from 2,6-dichloro-1-deazapurine (9). The new nucleosides proved to be good inhibitors of HIV-1 replication, the most active being the 2',3'-dideoxy

Potent and selective ligands for adenosine binding sites

A number of selective ligands for the different binding sites of adenosine have been synthesized and tested in several pharmacological models. The aim of these synthetic efforts is both to improve the knowledge of structure-activity relationships in the adenosine-related biological systems and to develop drugs from some of these molecules.

Synthesis and biological evaluation of N6-cycloalkyl derivatives of 1- deazaadenine nucleosides: A new class of anti-human immunodeficiency virus agents

A series of 1-deazaadenine nucleosides with the N6 nitrogen unsubstituted or bearing methyl or cycloalkyl substituents, with or without a chloro group in the 2-position, and with the glycosylic moiety being ribose (1-16), 2'- deoxyribose (17-32