1651865-13-2Relevant academic research and scientific papers
Outstanding effects on antithrombin activity of modified TBA diastereomers containing an optically pure acyclic nucleotide analogue
Scuotto,Persico,Bucci,Vellecco,Borbone,Morelli,Oliviero,Novellino,Piccialli,Cirino,Varra,Fattorusso,Mayol
, p. 5235 - 5242 (2014/07/08)
Herein, we report optically pure modified acyclic nucleosides as ideal probes for aptamer modification. These new monomers offer unique advantages in exploring the role played in thrombin inhibition by a single residue modification at key positions of the TBA structure.
