165266-71-7Relevant academic research and scientific papers
Side chain homologation of alanyl peptide nucleic acids: Pairing selectivity and stacking
Diederichsen, Ulf,Weicherding, Daniel,Diezemann, Nicola
, p. 1058 - 1066 (2007/10/03)
Alanyl peptide nucleic acids (alanyl-PNAs) are oligomers based on a regular peptide backbone with alternating configuration of the amino acids. All side chains are modified by covalently linked nucleobases. Alanyl-PNAs form very rigid, well defined, and l
Synthesis of N-Boc-α-Amino Acids with Nucleobase Residues as Building Blocks for the Preparation of Chiral PNA (Peptidic Nucleic Acids).
Lenzi, Alessandro,Reginato, Gianna,Taddei, Maurizio
, p. 1713 - 1716 (2007/10/02)
N-Boc-Glutamic acid α-benzyl ester was transformed into 4-bromo-2-(tert-butoxycarbonylamino)-butyric acid benzyl ester using the Barton-Crich protocol.This bromo derivative undergoes nucleophilic substitution with nucleobases to give optically active N-Bo
