16534-78-4 Usage
Uses
Used in Pharmaceutical Applications:
2,3,6-trihydroxybenzoic acid is used as a therapeutic agent for its potential role in preventing and treating various diseases. Its antioxidant properties make it a candidate for applications in cancer, diabetes, and cardiovascular diseases, where it may help mitigate oxidative stress and inflammation.
Used in Food Industry:
In the food industry, 2,3,6-trihydroxybenzoic acid is used as a food additive, capitalizing on its natural presence in nuts, fruits, and green tea. It contributes to the preservation and flavor enhancement of food products while also providing potential health benefits due to its antioxidant nature.
Used in Traditional Medicine:
2,3,6-trihydroxybenzoic acid is employed in traditional medicine, where its anti-inflammatory, neuroprotective, and antimicrobial effects are utilized for the treatment of various ailments. Its presence in natural remedies underscores its long-standing use in healthcare practices.
Used in Cosmetics:
2,3,6-trihydroxybenzoic acid is used as an ingredient in cosmetic products for its antioxidant and anti-inflammatory properties. It may help protect the skin from environmental damage and promote a healthier, more youthful appearance.
Used in Antimicrobial Applications:
Due to its antimicrobial effects, 2,3,6-trihydroxybenzoic acid is used in applications where controlling the growth of microorganisms is crucial, such as in the development of disinfectants and sanitizing agents. This can be particularly useful in healthcare settings and for general hygiene purposes.
Check Digit Verification of cas no
The CAS Registry Mumber 16534-78-4 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,6,5,3 and 4 respectively; the second part has 2 digits, 7 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 16534-78:
(7*1)+(6*6)+(5*5)+(4*3)+(3*4)+(2*7)+(1*8)=114
114 % 10 = 4
So 16534-78-4 is a valid CAS Registry Number.
16534-78-4Relevant academic research and scientific papers
Characterization of a 3-hydroxyanthranilic acid 6-hydroxylase involved in paulomycin biosynthesis
Ding, Yong,Wang, Min,Li, Jine,Li, Pengwei,Guo, Zhenyan,Chen, Yihua
, p. 8 - 14 (2021/02/02)
Paulomycins (PAUs) refer to a group of glycosylated antibiotics with attractive antibacterial activities against Gram-positive bacteria. They contain a special ring A moiety that is prone to dehydrate between C-4 and C-5 to a quinone-type form at acidic c
Functional annotation and characterization of 3-hydroxybenzoate 6-hydroxylase from Rhodococcus jostii RHA1
Montersino, Stefania,Van Berkel, Willem J.H.
experimental part, p. 433 - 442 (2012/07/14)
The genome of Rhodococcus jostii RHA1 contains an unusually large number of oxygenase encoding genes. Many of these genes have yet an unknown function, implying that a notable part of the biochemical and catabolic biodiversity of this Gram-positive soil actinomycete is still elusive. Here we present a multiple sequence alignment and phylogenetic analysis of putative R. jostii RHA1 flavoprotein hydroxylases. Out of 18 candidate sequences, three hydroxylases are absent in other available Rhodococcus genomes. In addition, we report the biochemical characterization of 3-hydroxybenzoate 6-hydroxylase (3HB6H), a gentisate-producing enzyme originally mis-annotated as salicylate hydroxylase. R. jostii RHA1 3HB6H expressed in Escherichia coli is a homodimer with each 47 kDa subunit containing a non-covalently bound FAD cofactor. The enzyme has a pH optimum around pH 8.3 and prefers NADH as external electron donor. 3HB6H is active with a series of 3-hydroxybenzoate analogues, bearing substituents in ortho- or meta-position of the aromatic ring. Gentisate, the physiological product, is a non-substrate effector of 3HB6H. This compound is not hydroxylated but strongly stimulates the NADH oxidase activity of the enzyme.
