Cas 165390-06-7,bis(2-methoxyethyl) 4-(2-chlorophenyl)-2,6-dimethyl-1,4-dihydropyridine-3,5-dicarboxylate

165390-06-7

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Basic information

Product Name: bis(2-methoxyethyl) 4-(2-chlorophenyl)-2,6-dimethyl-1,4-dihydropyridine-3,5-dicarboxylate
Synonyms: bis(2-methoxyethyl) 4-(2-chlorophenyl)-2,6-dimethyl-1,4-dihydropyridine-3,5-dicarboxylate
CAS NO:165390-06-7
Molecular Formula:
Molecular Weight: 423.894
EINECS: N/A
Product Categories: N/A

Chemical Properties

Melting Point: N/A
Boiling Point: N/A
Flash Point: N/A
Appearance: N/A
Density: N/A
Refractive Index: N/A
Storage Temp.: N/A
Solubility: N/A
CAS DataBase Reference: bis(2-methoxyethyl) 4-(2-chlorophenyl)-2,6-dimethyl-1,4-dihydropyridine-3,5-dicarboxylate(CAS DataBase Reference)
NIST Chemistry Reference: bis(2-methoxyethyl) 4-(2-chlorophenyl)-2,6-dimethyl-1,4-dihydropyridine-3,5-dicarboxylate(165390-06-7)
EPA Substance Registry System: bis(2-methoxyethyl) 4-(2-chlorophenyl)-2,6-dimethyl-1,4-dihydropyridine-3,5-dicarboxylate(165390-06-7)

Safety Data

Hazard Codes: N/A
Statements: N/A
Safety Statements: N/A
WGK Germany:
RTECS:
HazardClass: N/A
PackingGroup: N/A
Hazardous Substances Data: 165390-06-7(Hazardous Substances Data)

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Check Digit Verification of cas no

The CAS Registry Mumber 165390-06-7 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,6,5,3,9 and 0 respectively; the second part has 2 digits, 0 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 165390-06:
(8*1)+(7*6)+(6*5)+(5*3)+(4*9)+(3*0)+(2*0)+(1*6)=137
137 % 10 = 7
So 165390-06-7 is a valid CAS Registry Number.

165390-06-7Upstream product

165390-06-7Downstream Products

165390-06-7Relevant academic research and scientific papers

Synthesis, evaluation of pharmacological activity, and molecular docking of 1,4-dihydropyridines as calcium antagonists

Shaldam, Moataz Ahmed,El-Hamamsy, Mervat Hamed,Saleh, Dalia Osama,El-Moselhyb, Tarek Fathy

, p. 297 - 304 (2016)

1,4-Dihydropyridine (DHP) is an important class of calcium antagonist. It inhibits the influx of extracellular Ca2+ through L-type voltage-dependent calcium channels. Two series of nifedipine analogues were synthesized and evaluated as calcium

COMPOUNDS AND COMBINATIONS THEREOF FOR INHIBITING BETA-AMYLOID PRODUCTION AND METHODS OF USE THEREOF

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Page/Page column 121, (2010/11/29)

Provided are compounds which can be used in combination for treating diseases associated with a condition associated with cerebral accumulation of Alzheimer’s amyloid, such as Alzheimer’s disease. Also provided are methods of treating or reducing the risk of developing β-amyloid production, β-amyloid deposition, β-amyloid neurotoxicity (including abnormal hyperphosphorylation of tau) and microgliosis associated with cerebral accumulation of Alzheimer’s amyloid by administering therapeutically effective amounts of compounds which in combination can decrease β-amyloid production and capacitative calcium entry in cells. Further provided are methods for diagnosing diseases associated with cerebral accumulation of Alzheimer’s amyloid in animals or humans by administering diagnostically effective amounts of the compounds.

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