165401-59-2Relevant academic research and scientific papers
Synthesis of functionalized pyrimidine-4-thiones and derivatives of pyridopirimidine-5-one from monoacylketene aminals
Dorokhov, V. A.,Komkov, A. V.,Shashkova, E. M.,Bogdanov, V. S.,Bochkareva, M. N.
, p. 1848 - 1854 (1993)
Monoacylketene aminals containing an unsubstituted NH2 group react as C-nucleophiles with benzoyl isothiocyanate to give the corresponding thioamides which ubdergo cyclization by sodium methoxide in methanol to afford 6-R-amino-5-acetyl-2-phenyl-3H-pyrimi
Synthesis of 4-aminopyrazolo[3,4-d]pyrimidine derivatives from 5-acetyl-6-amino-4-methylsulfanyl- or 5-acetyl-6-amino-4- methylsulfonylpyrimidines
Komkov,Voronkova,Shashkov,Dorokhov
, p. 332 - 342 (2013/06/27)
Diacetyl ketene N,S-acetal was used for the synthesis of 5-acetyl-6-amino-4-methylsulfanylpyrimidines substituted at the exocyclic nitrogen atom, which were further oxidized with m-chloroperbenzoic acid to the corresponding methylsulfonylpyrimidines. Reac
